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                CD45 Mouse mAb
                EM1046
                規格: 價格:
                50 μl ¥1280.00
                100 μl ¥1980.00

                Overview

                Product name: CD45 Mouse mAb
                Human Swiss-Prot No.: P08575
                Reactivity: Human
                Alternative Names: B220, CD45R, GP180, L CA, LCA, Leukocyte common antigen, LY5, PTPRC, RPTPC, T200
                Source: Mouse
                Applications : WB
                Species reactivity: Human
                Species: Human
                Recommended dilutions: WB 1:2,000 IHC 1:200
                Immunogen: Synthetic Peptide
                Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
                Clonality: Monoclonal
                Isotype: IgG1
                Concentration: 1mg/ml
                Observed band: 147kDa
                GeneID(Human): 5788
                Cellular localization: Membrane
                Background: CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45.
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