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                CK19 Mouse mAb
                EM1051
                規格: 價格:
                50 μl ¥1280.00
                100 μl ¥1980.00

                Overview

                Product name: CK19 Mouse mAb
                Human Swiss-Prot No.: P08727
                Reactivity: Human, Rat, Mouse
                Alternative Names: Cytokeratin 19, K19, K1CS, keratin 19, KRT19
                Source: Mouse
                Applications : IHC
                Species reactivity: Human, Rat, Mouse
                Species: Human
                Recommended dilutions: IHC 1:200
                Immunogen: Synthetic Peptide
                Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
                Clonality: Monoclonal
                Isotype: IgG1
                Concentration: 1mg/ml
                Observed band: 44kDa
                GeneID(Human): 3880
                Cellular localization: Cytoskeleton,Cytosol
                Background: This protein is a member of the keratin family. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Keratin 19 is not expressed in hepatocytes, therefore, antibody to keratin 19 is useful in the identification of liver metastasis. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7.
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